CRISPR - Cas 9 Technology

Hello all!! Today I would like to make you aware of recently recognized CRISPR - Cas9 technology. The 2020 Nobel Prize in Chemistry was jointly awarded to Emmanuelle Charpentier and Jennifer A. Doudna for their work on the development of CRISPR-Cas9, a novel method for genome editing. Their work was described as “rewriting the code of life”. How CRISPR-Cas9 gene editing works? CRISPR stands for CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS and is a family of DNA sequences that are found in genomes of bacteria and other single-celled organisms called archaea. Cas9, which stands for CRISPR Associated Protein 9, is a protein that cuts DNA, providing the ability to modify the genome. The sequences also contain the genome of a bacteriophage (a virus that can infect a bacteria) - that has previously infected the bacteria or archaea. These DNA sequences can then be used to detect and destroy DNA from similar bacteriophages in the future and play a key role in antiviral immune syst...